decapeptide 12 peptide Decapeptide - Lipopeptide hydroquinone Decapeptide-12: A Deep Dive into its Properties and Applications in Skin Brightening

Lipopeptide Decapeptide-12 is a synthetic peptide that has garnered significant attention in the cosmetic and dermatological industries for its remarkable skin brightening capabilities作者：AT Kassim·2012·被引用次数：11—This prospective study evaluated the safety and efficacy ofdecapeptide-12in conjunction with an antioxidant cleanser, glycolic-acid containing facial .... Composed of ten amino acids with the sequence YRSRKYSSWY (or Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr), this oligopeptide functions primarily as a potent tyrosinase inhibitor.Price: 0 per gram. Sequence: H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH CAS #: NA If you require more than 5 grams, please Request a Quote. This mechanism is crucial for regulating melanin production, the pigment responsible for skin color, thereby addressing concerns like hyperpigmentation and uneven skin tone.

The efficacy of Decapeptide-12 has been extensively researched, positioning it as a promising alternative to traditional skin lightening agents.Decapeptide-12 (acetate) (YRSRKYSSWY) Studies have demonstrated that Decapeptide-12 is a significantly more potent tyrosinase inhibitor than hydroquinone, a widely used but often controversial skin lightening ingredient. For instance, research has shown it to be nearly 17-fold more potent than hydroquinone in inhibiting tyrosinase. Furthermore, unlike hydroquinone, Decapeptide-12 does not exhibit the same concerns regarding safety and irritation, making it a preferred choice for many cosmetic formulations. One study indicated that Decapeptide-12 achieved over 50% reduction in melanin content after twice-daily treatment for 16 weeks, highlighting its considerable efficacy.

The chemical structure of Decapeptide-12 is characterized by its molecular formula C65H90N18O17 and CAS number 137665-91-9. Its development as a cosmeceutical peptide is driven by its ability to target the root cause of pigmentation issues. By inhibiting the enzyme tyrosinase, Decapeptide-12 effectively reduces the synthesis of melanin. This targeted approach leads to a more even skin tone and a reduction in the appearance of dark spots, acne marks, sun damage, melasma, and age spots.

Beyond its primary function, Decapeptide-12 is also being explored for its potential roles in research related to melanogenesis, senescence, and inflammation. Its ability to modulate gene expression, such as sirtuin gene expression, further underscores its complex biological activity. The peptide is known for its high stability and skin penetration, designed for optimal delivery and effectivenessDecapaptide-12(Lumixyl) is a synthetic 10-amino acidpeptidewith the sequence YRSRKYSSWY or Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr, which acts to inhibit .... It is generally considered non-toxic and non-irritating, contributing to its favorable safety profile.

The market offers Decapeptide-12 in various purities and quantities, often with a purity of 99% or higher.decapeptide-12 For example, it is available in quantities such as 5g for approximately $1,200.00 and 25g for around $3,200D- Decapeptide-12 - ExperChem.00. Smaller research quantities, like 200mg, are also available. The price per gram can range, with some sources listing it at $390 per gram, especially for high-purity grades. For larger orders exceeding 5 grams, requesting a quote is standard practice.

When considering Decapeptide-12 for cosmetic applications, it is often formulated into products like skin brightening creams, serums, gels, and lotions. Its synergistic effect with other skincare ingredients, such as antioxidant cleansers and exfoliants like glycolic acid, has also been investigated, showing promising results in enhancing overall skin brightening efficacy. The development of Decapeptide-12 represents a significant advancement in the field of dermatological peptides, offering a safe and effective solution for achieving a more luminous and even complexionDecapeptide-12. Its scientific backing, coupled with a favorable safety profile compared to older treatments, solidifies its position as a key ingredient in modern skincare.